Advances in Molecular Pathology, 2019

Edited by Gregory J. Tsongalis, PhD, HCLD, CC, FNACB
Publication Date
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This issue of Advances in Molecular Pathology will provide a comprehensive review of the most current practices, trends, and developments in the field of Molecular Pathology. Publishing on an annual basis, the volume will be divided into 7 sections: Genetics, Hematopathology, Infectious Disease, Pharmacogenomics, Informatics, Solid tumors, and Identity/HLA. Led by Dr. Gregory Tsongalis of Dartmouth University, a team of experienced pathologists from institutions across the country oversee annual topic and expert author selection. 
ISBN 9780323709507
Author Information Edited by Gregory J. Tsongalis, PhD, HCLD, CC, FNACB, Professor, Vice Chair for Research, and Director of the Laboratory for Clinical Genomics and Advanced Technologies, Department of Pathology and Laboratory Medicine, Dartmouth Hitchcock Health System and the Audrey and Theodor Geisel School of Medicine, Lebanon, NH, USA”
Table of Content

Advances in Molecular Pathology Volume 2.1 Table of Contents


Molecular Pathology: Unraveling the Underlying Complexities of Human Disease

By Gregory J. Tsongalis


The Evolution of Constitutional Sequence Variant Interpretation

By Jessica Mester and Tina Pesaran

The Future of Clinical Diagnosis: Moving Functional Genomics Approaches to the Bedside

By Rini Pauly and Charles E. Schwartz

Genomic Data in the Electronic Health Record

By Nephi A. Walton, Darren K. Johnson, Thomas N. Person, and Srikar Chamala


Molecular Genetics in Myelodysplasia Outcomes Prognostication

By Lucas H. Rifkin and Eric Y. Loo

Assessing Measurable Residual Disease in Acute Myeloid Leukemia

By Daniel L. Duncan, Joshua F. Zeidner, and Nathan D. Montgomery

Philadelphia-Like Lymphoblastic Leukemia: Approach to Testing in Clinical Laboratories for Diagnosis, Prognosis, and Therapeutic Risk Assessment

By Michelle Afkhami

Myeloid Gene Panel Testing with Correlation to Updated Clinical Practice Guidelines

By Laura N. Toth and Daniel Babu

Infectious Disease

Impact of Molecular Diagnostics on Antimicrobial Stewardship

By Sheila M. Johnson, Mackenzie E. Collins, and Melissa B. Miller

Application of Next-Generation Sequencing in Public Health Epidemiology and Outbreak Investigation

By Anthony Tran and Marie-Claire Rowlinson

Next-Generation Sequencing Approaches to Predicting Antimicrobial Susceptibility Testing Results

By Rebecca Yee and Patricia J. Simner


Artificial Intelligence and Pharmacogenomics: A Timely Synergy for Individualizing Medicine

By Ravishankar K. Iyer, Arjun P. Athreya, Liewei Wang, and Richard M. Weinshilboum

The Evolution of DNA Sequencing in Pharmacogenomics

By Steven E. Scherer

Consumer-initiated Genetic Testing and Pharmacogenomics

By Ann M. Moyer and Linnea M. Baudhuin


Machine Learning in Biology and Medicine

By Javad Noorbakhsh, Harshpreet Chandok, R. Krishna Murthy Karuturi, and Joshy George

Solid Tumors

Clinical Use of Cell-Free DNA in Tumor Diagnostics

By Tejus A. Bale and Maria E. Arcila

Practical Concepts, Current Challenges, and Technological Advances in Clinical Next- Generation Sequencing Assays for Solid Tumors

By Mir B. Alikhan, Mustafa Al-Kawaaz, Karen Kaul, and Linda Sabatini

Evidence Builds for Tumor Mutation Burden as an Immunotherapy Biomarker

By Andrea Ferreira-Gonzalez


Human Leukocyte Antigen Typing Using High- Throughput DNA and RNA Sequencing and Application for Cell Line Identification

By Sebastian Boegel and John C. Castle

Expanding the Connectivity Map Concept as the Functional Look-Up Table for Systems Biology

By Bernard Kok Bang Lee, Sok Ching Cheong, and Aik Choon Tan


Publication Date 28-10-2019
Stock Status In Stock
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