Offering unique, comprehensive coverage of both basic science and clinical scenarios, Clinical Immunology: Principles and Practice, 6th Edition, brings you up to date with every aspect of this fast-changing field. It examines the molecular, cellular, and immunologic bases of immunologic diseases and their broader systemic implications; it also includes complete coverage of common and uncommon immunologic disorders. Updated with all the latest immunologic research and clinical implications, including breakthrough immunotherapies and molecular-based treatment protocols, this fully revised edition provides authoritative guidance from some of the most respected global leaders in immunology in one complete, well-illustrated volume.
Key Features
- Includes extensive revisions that reflect rapidly expanding research and clinical advances, including breakthrough drug and immunotherapies such as immune checkpoint inhibitors, immunotherapies for cancer, precision medicine, and transfusion medicine.
- Contains new chapters on COVID-19, immune responses, and the role of the immune system; immunoregulatory deficiencies; immune checkpoints; CAR T cells, including new cellular-based immunotherapy; gene therapy, including CRISPR and gene selection; and a clinically focused chapter on asthma.
- Provides new genetics content focused on data applications.
- Addresses notable advances in key areas such as the importance of the microbiota to normal immune system development and to the pathogenesis of immunologic and inflammatory diseases; relationships between the innate and adaptive immune systems; progress in rapid and cost-effective genomics; cell signaling pathways and the structure of cell-surface molecules; and many more.
- Covers hot topics such as the role of genetics and genomics in immune response and immunologic disease, atherosclerosis, recurrent fever syndromes, aging and deficiencies of innate immunity, the role of microbiota in normal immune system development and in the pathogenesis of immunologic and inflammatory diseases, and novel therapeutics.
- Features a user-friendly format with color-coded boxes highlighting critical information on Key Concepts, Clinical Pearls, Clinical Relevance, and Therapeutic Principles.
- Summarizes promising research and development anticipated over the next 5-10 years with "On the Horizon" boxes and discussions of translational research.
| ISBN | 9780702081668 |
|---|---|
| Product Format | Ebook |
| Publication Date | 2022 |
| Author Information | Edited by Robert R. Rich, MD, Professor of Medicine and Microbiology, University of Alabama at Birmingham School of Medicine, Birmingham, AL, USA; Thomas A. Fleisher, MD, FAAAAI, FACAAI, Adjunct Professor of Pediatrics, USUHA, Chief, Department of Laboratory Medicine, NIH Clinical Center, National Institutes of Health, Bethesda MD, USA; Harry W. Schroeder Jr., II, MD, PhD, Professor of Medicine, Microbiology, and Genetics, Division of Clinical Immunology and Rheumatology, Director, UAB Program in Immunology, University of Alabama at Birmingham, Birmingham, AL, USA; Cornelia M. Weyand, MD, PhD, Professor of Medicine, Stanford University School of Medicine, Department of Medicine: Immunology and Rheumatology, Stanford, CA, USA ; David B. Corry and Jennifer M. Puck |
| Table of Content | PART 1: Epidemiology, Growth and Development 1. Epidemiology and World-wide Impact of Visual Impairment in Children 2. Clinical Embryology and Developmental Biology of the Eye 3. Normal and Abnormal Visual Development 4. Milestones and Normative Data PART 2: Core Practice 5. Examination, History, and Special Tests in Pediatric Ophthalmology 6. Managing Refractive Errors in Children 7. Visual ElectrPediatric Visual Electrophysiology - objective measurement of visual function 8. Imaging the Child's Eye 9. Orbit and Visual Pathway Imaging 10. Genetics and Pediatric Ophthalmology PART 3: Infections, Allergic and External Eye Disorders 11. Ocular Manifestations of intrauterine infections 12. Conjunctivitis of the Newborn 13. Preseptal and Orbital Cellulitis 14. Endophthalmitis 15. External Eye Disease and the Oculocutaneous Disorders PART 4: Systematic Paediatric Ophthalmology Section A: Disorders of the Eye as a Whole 16. Disorders of the Eye as a Whole Section B: Lids, Brows and Oculoplastics 17. Lids: Congenital and acquired abnormalities - practical management 18. The Lacrimal System Section C: Orbit 19. The Management of Orbital Disease in Children 20. Lid and orbital infantile periocular hemangiomas (capillary hemangiomas) and other vascular diseases 21. Neurogenic Tumors of the Orbit 22. Orbital Rhabdomyosarcoma 23. Other Mesenchymal Abnormalities 24. Metastatic, Secondary & Lacrimal Gland Tumors 25. Histiocytic, Haematopoietic and Lymphoproliferative Disorders 26. Craniofacial Abnormalities 27. Cystic Lesions and Ectopias 28. Inflammatory Disorders Section D: External Disease and Anterior Segment 29. Conjunctiva 30. Conjunctival Tumors 31. Anterior Segment Developmental Anomalies 32. Corneal abnormalities in childhood 33. Corneal surgery 34. The Lens 35. Childhood Cataracts 36. Childhood Glaucoma Section E: The Uvea 37. Pediatric Iris Disorders 38. Aniridia Syndrome 39. Uveitis 40. Albinism Section F: Retinal & Vitreous Disorders 41. Vitreous 42. Retinoblastoma 43. Retinopathy of Prematurity: Pathophysiology and screening 44. Current Treatment of Retinopathy of Prematurity 45. Inherited retinal disorders 46. Retinal Dystrophies with Systemic Associations and the Retinal Ciliopathies 47. Inherited Macular Dystrophies 48. Congenital pigmentary and vascular abnormalities of the retina 49. Retinal flecks, dots and crystals 50. Acquired and other retinal disorders (including Juvenile X-Linked Retinoschisis) 51. Retinal Detachment in Childhood Section G: Neural Visual Systems 52. The Pupil 53. Congenital Anomalies of the Optic Discs 54. Hereditary Optic Neuropathies 55. Other Acquired Optic Disc Abnormalities in Children 56. Demyelinating, Inflammatory, and Infectious Optic Neuropathies 57. The Optic Chiasm 58. Headache in Children 59. Raised Intracranial Pressure 60. The Brain and Cerebral Visual Impairment PART 5: Selected Topics in Pediatic Ophthalmology 61. Delivering Bad News 62. Common Issues arising in Children with Visual Impairment 63. Visual conversion disorders and fabricated or exaggerated symptoms in children 64. Dyslexia 65. Neurometabolic Disease and the Eye 66. Leukemia 67. Mitochondrial disorders 68. Phakomatoses 69. Neurofibromatosis Type 1 and 2 70. Accidental Trauma in Children 71. Child Maltreatment, Abusive Head Trauma and the Eye 72. Refractive Surgery in Children PART 6: Amblyopia, Strabismus and Eye Movements Section A: The Fundamentals of Strabismus and Amblyopia 73. Binocular Vision 74. Amblyopia: the basics, the questions, and the practical management 75. Anatomy of Strabismus 76. The Orthoptic Evaluation Section B: Esotropias 77. Infantile Esotropias 78. Accommodative Esotropias 79. Special Esotropias (acute comitant, myopia-associated and microtropia) Section C: Exotropias 80. Intermittent Exotropia 81. Special Forms of Comitant Exotropia Section D: Vertical, "Pattern" Strabismus and Abnormal Head Postures 82. Vertical Strabismus 83. "A," "V," and other pattern strabismus Section E: "Neurological" Strabismus 84. Congenital Cranial Dysinnervation Disorders 85. Ocular Motor Nerve Palsies 86. Myasthenia Gravis Section F: Strabismus Treatment 87. Strabismus: non-surgical treatment 88. Strabismus Surgery 89. Complications in Strabismus Surgery Section G: Nystagmus and Eye Movements 90. Nystagmus in childhood 91. Supranuclear Eye Movement Disorders: Acquired and Neurological Nystagmus PART 7: Common Practical Problems in a Paediatric Ophthalmology and Strabismus Practice 92. "I think my baby can't see!" 93. "My baby's got a red eye, doctor!" 94. "My child keeps blinking and closing his eye" 95. "My child seems to hate the bright light" 96. My child's eyes keep watering!" 97. Proptosis at different ages 98. "My child's teacher says she can't see properly!" 99. The child with a dual sensory loss (deafblind) 100. "My little girl tells me she sees strange things" 101. Wobbly Eyes In Infancy 102. Abnormal Head Postures in Children 103. Hand Defects and the Eye 104. Optimizing Compliance In Patching Therapy 105. Vision Screening |
| Publication Date | 23-08-2022 |
| deltacomm1code | Electronic Book |
