Diagnostic Pathology: Placenta E-Book, 2nd Edition

By Amy Heerema-McKenney, MD
Publication Date
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Part of the highly regarded Diagnostic Pathology series, this updated volume covers all aspects of placental pathology and the critical role the placenta plays in the unique interface between mother and fetus. Concise, focused chapters, supported by tables, diagrams, and photographs, keep you up-to-date with evolving changes in the questions and issues concerning both the fetus/infant and the mother. This revised edition is ideal for pathologists at all levels of experience and training for use as a quick reference and as an efficient review to improve knowledge and skills.

Key Features
  • Provides clear and concise information on gross and microscopic changes of the placenta, common diagnoses, and placental evaluation in special circumstances
  • Includes updated terminology and diagnostic criteria, new recommendations for the use of molecular techniques such as SNP array or whole genome sequencing for evaluation of stillbirth, and more images to illustrate challenging diagnoses
  • Contains new chapters on pathology of maternal mortality, complications of twin pregnancies, and hypoxic-ischemic encephalopathy, as well as expanded chapters on gestational trophoblastic disease and new coverage of twin anemia polycythemia sequence (TAPS)
  • Covers pregnancy complications such as preeclampsia, intrauterine growth restriction, and multiple gestations, highlighting placental findings, key correlates, relevant fetal organ pathology, and the pathology of the postpartum hysterectomy
  • Time-saving reference features include bulleted text, annotated images, reference tables for placental evaluation, and sample templates useful for gross and microscopic placental description
ISBN 9780323609722
Product Format Ebook
Publication Date 2019
Author Information By Amy Heerema-McKenney, MD, Perinatal Pathologist, Cleveland Clinic Institute of Pathology and Laboratory Medicine, Cleveland, Ohio
Table of Content

Overview of Gross and Microscopic Changes

Umbilical Cord

Gross Evaluation and Normal Histology of Umbilical Cord


Umbilical Cord Edema and Thinning

Histopathologic Changes of Umbilical Cord

Extraplacental Membranes

Gross Evaluation and Normal Histology of Membranes

Histopathologic Changes of Membranes

Chorionic Plate

Gross Evaluation and Normal Histology of Chorionic Plate

Histopathologic Changes of Chorionic Plate

Stem Villi

Gross Evaluation and Normal Histology of Stem Villi

Histopathologic Changes of Stem Villi

Chorionic Villi

Gross Evaluation and Normal Histology of Chorionic Villi

Histopathologic Changes of Chorionic Villi

Septa, Intervillous Space, and Basal Plate

Gross Evaluation and Normal Histology of Septa, Intervillous Space, and Basal Plate

Histopathologic Changes of Septa, Intervillous Space, and Basal Plate


Gross Evaluation and Normal Histology of Decidua

Histopathologic Changes of Decidua

Placental Diagnoses


Meconium-Stained Placenta

Amniotic Fluid Infection Sequence

Amniotic Fluid Infection Sequence (Maternal and Fetal Inflammatory Response)

Group B Streptococcus

Other Bacterial and Mycobacterial Species


Placental Infections With Villitis and Other Findings


Parvovirus B19

Herpes Simplex Virus

Other Viruses




Chronic Inflammatory Lesions

Cellular Composition of Chronic Inflammatory Lesions

Chronic Villitis and Intervillositis

Basal Chronic Villitis and Chronic Deciduitis

Chronic Chorioamnionitis

Eosinophilic/T-Cell Chorionic Vasculitis

Massive Perivillous Fibrin Deposition and Maternal Floor Infarction

Massive Perivillous Fibrin Deposition and Maternal Floor Infarction

Fetal Vasculopathy

Large Vessel Fetal Vascular Occlusion

Distal Villous Lesions Associated With Fetal Vascular Occlusion

Placental Abruption

Acute Abruption and Retroplacental Hematoma

Chronic Abruption

Villous Hypervascular Lesions




Gestational Trophoblastic Disease and Metastatic Tumors

Hydropic Degeneration Mole

Partial Hydatidiform Mole

Complete Hydatidiform Mole


Placental Site Nodule and Exaggerated Placental Site

Placental Site Trophoblastic Tumor and Epithelioid Trophoblastic Tumor

Metastatic Tumors

Placental Mesenchymal Dysplasia

Placental Mesenchymal Dysplasia

Placental Evaluation in Special Circumstances

Gestational Diabetes

Gestational Diabetes


Distal Villous Immaturity

Preeclampsia and Uteroplacental Malperfusion

Preeclampsia and Related Hypertensive Disorders

Small for Gestational Age Placenta

Distal Villous Hypoplasia

Maternal Decidual Vasculopathy


Extravillous Cytotrophoblast Cysts

Laminar Decidual Necrosis

Fetal-Maternal Hemorrhage

Fetal-Maternal Hemorrhage

Intrauterine Growth Restriction

Placental Causes of Poor Fetal Growth


Placental Findings in Premature Birth

Abnormal Placental Implantation

Placenta Accreta

Intrauterine Fetal Demise

1st-Trimester Pregnancy Loss

2nd-Trimester Fetal Demise

3rd-Trimester Fetal Demise

Recurrent Pregnancy Loss

In Utero Demise to Delivery Interval Changes

Hypoxic Ischemic Encephalopathy

Multiple Gestations

Complications of Monochorionic Monoamniotic Twin Gestations

Twin Growth Discrepancy

Twin-Twin Transfusion Syndrome

Twin Anemia-Polycythemia Sequence

After In Utero Intervention for Twin-Twin Transfusion Syndrome

Triplet and Higher Order Placenta

Maternal Complications of Pregnancy

Maternal Mortality

Evaluation of Postpartum Hysterectomy

Postpartum Hemorrhage


Reference Charts for Placental Evaluation

Weights for Singleton Placentas

Weights for Twin Placentas

Weights for Triplet Placentas

Reference Values for Fetal and Placental Growth in Early Pregnancy

Sample Templates for Placental Evaluation

Singleton Placenta Gross Evaluation

Twin Placenta Gross Evaluation

Placenta Microscopic Evaluation

Placenta Triage

Publication Date 28-08-2019
Pages 496
deltacomm1code Electronic Book
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