Kelley and Firestein's Textbook of Rheumatology E-Book , 10th Edition

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By Gary S. Firestein, MD, Ralph Budd, Sherine E Gabriel, MD, MSc, Iain B. McInnes, PhD, FRCP, FRSE and James R O'Dell, MD
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  • An ideal balance of the basic science you need to know and how to apply that information to clinical practice.
  • An integrated chapter format allows you to review basic science advances and their clinical implications in one place and get dependable, evidence-based guidance for the full range of rheumatologic diseases and syndromes.
  • Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability.

Consult the definitive resource in rheumatology for an in-depth understanding of scientific advances as they apply to clinical practice. Masterfully edited by Drs. Gary S. Firestein, Ralph C. Budd, Sherine E. Gabriel, Iain B. McInnes, and James R. O'Dell, and authored by internationally renowned scientists and clinicians in the field, Kelley and Firestein's Textbook of Rheumatology, 10th Edition, delivers the knowledge you need for accurate diagnoses and effective patient care. From basic science, immunology, anatomy, and physiology to diagnostic tests, procedures, and specific disease processes, this state-of-the-art reference provides a global, authoritative perspective on the manifestations, diagnosis and treatment of rheumatic diseases.

Key Features
  • An ideal balance of the basic science you need to know and how to apply that information to clinical practice.
  • An integrated chapter format allows you to review basic science advances and their clinical implications in one place and get dependable, evidence-based guidance for the full range of rheumatologic diseases and syndromes.
  • Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability.
ISBN 9780323414944-vst
Author Informaiton By Gary S. Firestein, MD, Distinguished Professor of Medicine, Dean and Associate Vice Chancellor of Translational Medicine, University of California San Diego School of Medicine, La Jolla, California; Ralph C. Budd, MD, Professor of Medicine and Microbiology and Molecular Genetics, Director, Vermont Center for Immunology and Infectious Diseases, University of Vermont College of Medicine Distinguished University Professor, The University of Vermont College of Medicine, Burlington, Vermont; Sherine E Gabriel, MD, MSc, Professor and Dean, Rutgers Robert Wood Johnson Medical School, CEO, Robert Wood Johnson Medical Group, Emeritus Professor, Mayo Clinic, New Brunswick, New Jersey ; Iain B. McInnes, PhD, FRCP, FRSE, Director, Institute of Infection, Immunity, and Inflammation College of Medical, Veterinary, and Life Sciences Glasgow Biomedical Research Centre University of Glasgow Glasgow, United Kingdom and James R O'Dell, MD, Bruce Professor and Vice Chairman of Internal Medicine, University of Nebraska Medical Center, Chief of Rheumatology, Department of Medicine, Omaha Veterans Affairs, Omaha, Nebraska
Table of Content

1 Biology of the Normal Joint

2 Synovium

3 Cartilage and Chondrocytes

4 Biology, Physiology, and Morphology of Bone

5 Muscle: Anatomy, Physiology, and Biochemistry

6 Biomechanics

7 Regenerative Medicine and Tissue Engineering

8 Proteinases and Matrix Degradation

9 Dendritic Cells: General Overview and Role in Autoimmunity

10 Mononuclear Phagocytes

11 Neutrophils

12 T Lymphocytes

13 B Cells

14 Fibroblasts and Fibroblast-like Synoviocytes

15 Mast Cells

16 Platelets

17 Innate Immunity

18 Adaptive Immunity and Organization of Lymphoid Tissues

19 Autoimmunity

20 Metabolic Regulation of  Immunity

21 Genetics of Rheumatic Diseases

22 Epigenetics of Rheumatic Diseases

23 Complement System

24 Prostaglandins, Leukotrienes, and Related Compounds

25 Cell Recruitment and Angiogenesis

26 Cytokines

27 Principles of Signaling

28 Immunological Repercussions of Cell Death

29 Experimental Models for Rheumatoid Arthritis

30 Neuronal Regulation of Pain and Inflammation

31 Clinical Research Methods in Rheumatic Disease

32 Economic Burden of  the Rheumatic Diseases

33 Assessment of Health Outcomes

34 Biologic Markers in Clinical Trials and Clinical Care

35 Occupational and Recreational MSK Disorders

36 Cardiovascular Risk in Inflammatory Rheumatic Disease

37 Cancer Risk in Rheumatic Diseases

38 Introduction to Physical Medicine, Physical Therapy and Rehabilitation

39 Pregnancy and Rheumatic Diseases

40 History and Physical Examination of the Musculoskeletal System

41 Acute Monoarthritis

42 Evaluation and Differential Diagnosis of Polyarthritis

43 The Skin and Rheumatic Diseases

44 The Eye and Rheumatic Diseases

45 Neck Pain

46 Shoulder Pain

47 Low Back Pain

48 Hip and Knee Pain

49 Foot andAnkle Pain

50 Hand and Wrist Pain

51 Temporomandibular Joint Pain

52 Fibromyalgia

53 Synovial Fluid Analysis, Synovial Biopsy, and Synovial Pathology

54 Arthrocentesis and Injection of Joints and Soft Tissue

55 Anti-nuclear Antibodies

56 Autoantibodies in Rheumatoid Arthritis

57 Acute Phase Reactants and the Concept of Inflammation

58 Imaging in Rheumatic Diseases

59 Biology and its Therapeutic Targeting of Prostanoids

60 Glucocorticoid Therapy

61 Traditional DMARDs: Methotrexate, Leflunomide, Sulfasalazine, and Hydroxychloroquine and Combination Therapies

62 Immunosuppressive Drugs

63 Anti-cytokine Therapies

64 Cell Targeted Biologics and Emerging Targets: Rituximab, Abatacept, and Other Biologics

65 Novel Intra-cellular Targeting Agents in Rheumatic Disease

66 Urate-Lowering Therapy

67 Analgesic Agents in Rheumatic Disease

68 Nutrition and Rheumatic Diseases

69 Etiology and Pathogenesis of Rheumatoid Arthritis

70 Clinical Features of Rheumatoid Arthritis

71 Treatment of Rheumatoid Arthritis

72 Early Synovitis and Early Undifferentiated Arthritis

73 Sjogren's Syndrome

74 Etiology and Pathogenesis of Spondyloarthritis

75 Ankylosing Spondylitis

76 Undifferentiated Spondyloarthritis

77 Psoriatic Arthritis

78 Enteropathic Arthritis

79 Etiology and Pathogenesis of SLE

80 Clinical Features of SLE

81 Treatment of SLE

82 Anti-phospholipid Syndrome

83 Etiology and Pathogenesis of Scleroderma

84 Clinical Features and Treatment of Scleroderma

85 Inflammatory Diseases of Muscle and Other Myopathies

86 Overlap Syndromes

87 Classification and Epidemiology of Systemic Vasculitis

88 Giant Cell Arteritis, Polymyalgia Rheumatica, and Takayasu's Arteritis

89 Anti-neutrophil Cytoplasmic Antibody-Associated Vasculitis

90 Polyarteritis Nodosa and Related Disorders

91 Immune Complex-Mediated Small-Vessel Vasculitis

92 PrimaryAngiitis of the Central Nervous System

93 Bechet's Disease

94 Etiology and Pathogenesis of Gout and Hyperuricemia

95 Clinical Features and Treatment of Gout

96 Calcium Crystal Disease: Calcium Pyrophosphate Dihydrate and Basic Calcium Phosphate

97 Familial Autoinflammatory Syndromes

98 Pathogenesis of Osteoarthritis

99 Clinical Features of Osteoarthritis

100 Treatment of Osteoarthritis

101 Metabolic Bone Disease

102 Proliferative Bone Disease

103 Osteonecrosis

104 Relapsing Polychondritis

105 Heritable Diseases of Connective Tissue

106 Etiology and Pathogenesis of Juvenile Idiopathic Arthritis

107 Clinical Features and Treatment of Juvenile Inflammatory Arthritis

108 Pediatric SLE, Juvenile Dermatomyositis, Scleroderma and Vasculitis

109 Bacterial Arthritis

110 Lyme Disease

111 Mycobacterial Infections of Bones and Joints

112 Fungal Infections of Bones and Joints

113 Rheumatic Manifestations of HIV Infection

114 Viral Arthritis

115 Rheumatic Fever and Post-streptococcal Arthritis

116 Amyloidosis

117 Sarcoidosis

118 Hemachromotosis

119 Hemophilic Arthropathy

120 Rheumatic Manifestations of Hemoglobinopathies

121 IgG4-Related Disease

122 Arthritis Accompanying Endocrine and Metabolic Disorders

123 Musculoskeletal Syndromes in Malignancy

124 Tumors and Tumor-like Lesions of Joints and Related Structures

Publication Date 21-06-2016
Pages 275

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