Molecular Oncology Diagnostics, An Issue of the Clinics in Laboratory Medicine, E-Book

Edited by Fei Dong, MD
Publication Date
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In this issue of Clinics in Laboratory Medicine, guest editor Dr. Fei Dong brings his considerable expertise to the topic of Molecular Oncology Diagnostics. Top experts in the field review current practices in molecular oncology diagnostics, highlighting the rapid clinical adoption of next generation sequencing techniques. The articles address key laboratory considerations in the molecular testing of cancer specimens and the impact of advanced testing strategies on patient care. 

Key Features
  • Contains 15 practice-oriented topics including utility of single gene testing in cancer specimens; analytical principles of cancer next generation sequencing; principles and validation of bioinformatics pipelines for cancer next generation sequencing; panel sequencing for targeted therapy selection in solid tumors; and more. 

  • Provides in-depth clinical reviews on molecular oncology diagnostics, offering actionable insights for clinical practice. 

  • Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews. 

ISBN 9780323849371
Product Format Ebook
Publication Date 2022
Author Information Edited by Fei Dong, MD, Associate Pathologist , Brigham and Women's Hospital , Assistant Professor , Harvard Medical School
Table of Content Panel Sequencing for Targeted Therapy Selection in Solid Tumors
Molecular Diagnostic Testing for Hematopoietic Neoplasms: Linking Pathogenic Drivers to Personalized Diagnosis
Special Considerations in the Molecular Diagnostics of Pediatric Neoplasms
Specimen Considerations in Molecular Oncology Testing
Utility of Single-Gene Testing in Cancer Specimens
Analytical Principles of Cancer Next Generation Sequencing
Principles and Validation of Bioinformatics Pipeline for Cancer Next-Generation Sequencing
Best Practice for Clinical Somatic Variant Interpretation and Reporting
Molecular Detection of Oncogenic Gene Rearrangements
Copy Number Analysis in Cancer Diagnostic Testing
Molecular Biomarkers of Response to Cancer Immunotherapy
When Tissue Is the Issue: Expanding Cell-Free DNA "Liquid Biopsies” to Supernatants and Nonplasma Biofluids
Germline Testing for the Evaluation of Hereditary Cancer Predisposition
Publication Date 23-09-2022
Pages 240
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