Toxicology Handbook, 3rd Edition

Author
By Jason Armstrong, MD FACEM and Ovidiu Pascu, MD FACEM
ISBN
9780729542241
Publication Date
19-03-2015
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Paperback
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    • Guides clinicians through drug administration and treatment
    • Includes 'handy tips' and 'pitfalls'
    • Incorporates drug dosages and administration are based on current pharmacological regulations

    Toxicology Handbook is a practical evidence-based guide on the care of the poisoned patient.

    This concise text is informed by the latest clinical research and takes a rigorous and structured risk assessment-based approach to decision making in the context of clinical toxicology.

    It assists the clinician to quickly find information on poisons, toxins, antidotes, envenomings and antivenoms and determine the appropriate treatment for the acutely poisoned patient.


    Key Features
      • Guides clinicians through drug administration and treatment
      • Includes 'handy tips' and 'pitfalls'
      • Incorporates drug dosages and administration are based on current pharmacological regulations
      ADDITIONAL INFORMATION
      ISBN 9780729542241
      Product Format Book
      Publication Date 2015
      Author Information By Jason Armstrong, MD FACEM and Ovidiu Pascu, MD FACEM, Consultant Emergency Physician and Clinical Toxicologist, Sir Charles Gairdner Hospital, Perth, WA Poisons Information Centre; Clinical Senior Lecturer in Emergency Medicine, University of Western Australia, WA, Australia
      Table of Content

      CHAPTER 1 APPROACH TO THE POISONED PATIENT
      1.1 Overview 
      1.2 Resuscitation 
      1.3 Risk assessment 
      1.4 Supportive care and monitoring 
      1.5 Investigations 
      1.6 Gastrointestinal decontamination 
      1.7 Enhanced elimination 
      1.8 Antidotes 
      1.9 Disposition

      CHAPTER 2 SPECIFIC CONSIDERATIONS
      2.1 Approach to snakebite 
      2.2 Approach to mushroom poisoning 
      2.3 Approach to plant poisoning 
      2.4 Coma 
      2.5 Hypotension 
      2.6 Seizures 
      2.7 Delirium and agitation 
      2.8 Serotonin syndrome 
      2.9 Anticholinergic syndrome 
      2.10 Cholinergic syndrome 
      2.11 Neuroleptic malignant syndrome 
      2.12 Alcohol use disorder 
      2.13 Amphetamine use disorder 
      2.14 Opioid use disorder 
      2.15 Sedative-hypnotic use disorder 
      2.16 Solvent abuse 
      2.17 Body packers and stuffers 
      2.18 Osmolality and the osmolar gap 
      2.19 Acid - base disorders 
      2.20 The 12-lead ECG in toxicology 
      2.21 Poisoning during pregnancy and lactation 
      2.22 Poisoning in children
      2.23 Poisoning in the elderly 

      CHAPTER 3 SPECIFIC TOXINS
      3.1 Alcohol: Ethanol 
      3.2 Alcohol: Ethylene glycol 
      3.3 Alcohol: Isopropanol (isopropyl alcohol) 
      3.4 Alcohol: Methanol (methyl alcohol) 
      3.5 Alcohol: Other toxic alcohols 
      3.6 Amiodarone 
      3.7 Amisulpride 
      3.8 Amphetamines 
      3.9 Angiotensin converting enzyme inhibitors 
      3.10 Anticoagulant rodenticides 
      3.11 Anticonvulsants: Newer agents 
      3.12 Antihistamines (non-sedating) 
      3.13 Antihistamines (sedating) 
      3.14 Arsenic
      3.15 Baclofen 
      3.16 Barbiturates 
      3.17 Benzodiazepines 
      3.18 Benztropine 
      3.19 Beta-blockers 
      3.20 Bupropion 
      3.21 Button batteries 
      3.22 Calcium channel blockers 
      3.23 Cannabinoids (marijuana) 
      3.24 Carbamazepine 
      3.25 Carbon monoxide 
      3.26 Chloroquine and hydroxychloroquine 
      3.27 Chloral hydrate 
      3.28 Clonidine 
      3.29 Clozapine 
      3.30 Cocaine 
      3.31 Colchicine 
      3.32 Corrosives 
      3.33 Cyanide
      3.34 Digoxin: Acute overdose
      3.35 Digoxin: Chronic poisoning 
      3.36 Diphenoxylate-atropine 
      3.37 Gamma-hydroxybutyrate (GHB) 
      3.38 Glyphosate 
      3.39 Hydrocarbons 
      3.40 Hydrofluoric acid 
      3.41 Hydrogen peroxide 
      3.42 Insulin 
      3.43 Iron 
      3.44 Isoniazid 
      3.45 Lead 
      3.46 Lithium: Acute overdose
      3.47 Lithium: Chronic poisoning 
      3.48 Local anaesthetic agents 
      3.49 Mercury 
      3.50 Metformin 
      3.51 Methotrexate 
      3.52 Mirtazapine 
      3.53 Monoamine oxidase inhibitors (MAOIs) 
      3.54 Newer oral anticoagulants (NOACs)
      3.55 Non-steroidal anti-inflammatory drugs (NSAIDs) 
      3.56 Olanzapine 
      3.57 Opioids 
      3.58 Organochlorines 
      3.59 Organophosphorus agents (organophosphates and carbamates) 
      3.60 Paracetamol: Acute overdose 
      3.61 Paracetamol: Modified-release formulations
      3.62 Paracetamol: Repeated supratherapeutic ingestion 
      3.63 Paraquat 
      3.64 Phenothiazines and butyrophenones (antipsychotic agents) 
      3.65 Phenytoin 
      3.66 Potassium chloride 
      3.67 Quetiapine 
      3.68 Quinine 
      3.69 Risperidone 
      3.70 Salicylates 
      3.71 Selective serotonin reuptake inhibitors (SSRIs) 
      3.72 Strychnine 
      3.73 Sylfonyureas
      3.74 Theophylline 
      3.75 Thyroxine 
      3.76 Tramadol 
      3.77 Tricyclic antidepressants (TCAs) 
      3.78 Valproic acid (sodium valproate) 
      3.79 Venlafaxine and desvenlafaxine 
      3.80 Warfarin 

      CHAPTER 4 ANTIDOTES
      4.1 Atropine 
      4.2 Calcium 
      4.3 Cyproheptadine 
      4.4 Desferrioxamine 
      4.5 Dicobalt edetate 
      4.6 Digoxin immune Fab 
      4.7 Dimercaprol 
      4.8 Ethanol 
      4.9 Flumazenil 
      4.10 Folinic acid 
      4.11 Fomepizole 
      4.12 Glucose 
      4.13 Hydroxocobalamin 
      4.14 Insulin (high dose) 
      4.15 Intravenous lipid emulsion 
      4.16 Methylene blue 
      4.17 N-acetylcysteine 
      4.18 Naloxone 
      4.19 Octreotide 
      4.20 Penicillamine 
      4.21 Physostigmine 
      4.22 Pralidoxime 
      4.23 Pyridoxine 
      4.24 Sodium bicarbonate 
      4.25 Sodium calcium edetate 
      4.26 Sodium thiosulfate 
      4.27 Succimer 
      4.28 Vitamin K 

      CHAPTER 5 ENVENOMINGS
      5.1 Black snake
      5.2 Brown snake 
      5.3 Death adder 
      5.4 Tiger snake group 
      5.5 Taipan 
      5.6 Sea snake 
      5.7 Australian scorpions 
      5.8 Bluebottle jellyfish (Physalia species) 
      5.9 Stonefish 
      5.10 Box jellyfish (Chironex fleckeri) 
      5.11 Irukandji syndrome 
      5.12 Blue-ringed octopus 
      5.13 Redback spider 
      5.14 Funnel-web (big black) spider
      5.15 White-tailed spider 
      5.16 Ticks 

      CHAPTER 6 ANTIVENOMS
      6.1 CSL Black Snake Antivenom 
      6.2 CSL Brown Snake Antivenom 
      6.3 CSL Death Adder Antivenom 
      6.4 CSL Tiger Snake Antivenom 
      6.5 CSL Taipan Antivenom 
      6.6 CSL Sea Snake Antivenom 
      6.7 CSL Polyvalent Snake Antivenom 
      6.8 CSL Stonefish Antivenom 
      6.9 CSL Box Jellyfish Antivenom 
      6.10 CSL Redback Spider Antivenom 
      6.11 CSL Funnel-web Spider Antivenom 

      APPENDICES
      Appendix 1 Poison Information Telephone Numbers
      Appendix 2 Example ECGs
      Appendix 3 Conversion factors and therapeutic ranges for important toxins
      Appendix 4 Alcohol pathways
      Appendix 5 Therapeutic over-warfarinisation
      Appendix 6 Management of allergic reactions to antivenoms
       

      Publication Date 19-03-2015
      Pages 544
      Trim 190 x 125mm
      Stock Status In Stock
      deltacomm1code Books
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