Stroke , 6th Edition :Pathophysiology, Diagnosis, and Management

Author By James C. Grotta, MD, Gregory W Albers, MD, Joseph P Broderick, MD, Scott E Kasner, MD, MSCE, FRCP, Eng H Lo, PhD, A David Mendelow, MB BCh, FRCS, PhD, Ralph L Sacco, MD MS FAHA FAAN and Lawrence KS Wong, MD, FRCP



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Offered in print, online, and downloadable formats, this updated edition of Stroke: Pathophysiology, Diagnosis, and Management delivers convenient access to the latest research findings and management approaches for cerebrovascular disease. Picking up from where J. P. Mohr and colleagues left off, a new team of editors - Drs. Grotta, Albers, Broderick, Kasner, Lo, Mendelow, Sacco, and Wong - head the sixth edition of this classic text, which is authored by the world's foremost stroke experts.


      • Data from late-breaking endovascular trials equips you with recent findings.
      • Includes comprehensive coverage of advances in molecular biology of cell death; risk factors and prevention; advances in diagnostics and stroke imaging; and therapeutic options, including a thorough review of thrombolytic agents and emerging data for endovascular therapy.
      • Features brand-new chapters on Intracellular Signaling: Mediators and Protective Responses; The Neurovascular Unit and Responses to Ischemia; Mechanisms of Cerebral Hemorrhage; Stroke Related to Surgery and Other Procedures; Cryptogenic Stroke; and Interventions to Improve Recovery after Stroke.
      • Highlights new information on genetic risk factors; primary prevention of stroke; infectious diseases and stroke; recovery interventions such as robotics, brain stimulation, and telerehabilitation; and trial design.
      • Details advances in diagnostic tests, such as ultrasound, computed tomography (including CT angiography and CT perfusion), MRI (including MR perfusion techniques), and angiography.
      • Includes extracted and highlighted evidence levels.
      • Expert Consult eBook version included with print purchase. This enhanced eBook experience allows you to search all of the text, figures, and references on a variety of devices. The content can also be downloaded to tablets and smart phones for offline use.


      • Comprehensive, expert clinical guidance enables you to recognize the clinical manifestations of stroke, use the latest laboratory and imaging studies to arrive at a diagnosis, and generate an effective medical and surgical treatment plan.
      • Abundant full-color CT images and pathology slides help you make efficient and accurate diagnoses.


      "Authoritative, eminently readable, and current."-Journal of Neurosurgery

      "[F]or depth of coverage of individual subjects and as a reference for cerebrovascular diseases, [Stroke] has become the standard."-Annals of Internal Medicine

      "Should be part of the libraries of all [those] who deal with cerebrovascular disease." -JAMA

      "Updating such a big reference work is a huge task, and by and large the editors have succeeded in their task. They have assembled many very distinguished authors and put together a pretty comprehensive reference work."
      -Journal of Neurology Neurosurgery and Psychiatry

      Reviews of previous edition.
      "There are sections on pathophysiology, epidemiology, clinical manifestation and individual sections dealing with specific pathological conditions explaining each in great depth. In addition, it has extensive sections devoted to therapy including medical, interventional and surgical. All this makes the book a one-stop-shop for stroke. As a result, it is a work that will prove valuable to a wide range of clinicians involved with providing stroke services, including stroke physicians, acute care physicians, researchers, public health physicians and those involved with rehabilitation medicine...In comparison to the previous editions, the book has definite a advantages in the form of picture quality and web access. It is excellent value for the price as a reference book for stroke, not radiology specific. The book would find its place in a departmental radiology library. Overall, an excellent, up-to-date reference volume."
      RAD, May 2012


      By James C. Grotta, MD, Director, Stroke Program, Memorial Hermann - Texas Medical Center; Professor of Neurology; Chairman, Department of Neurology, University of Texas Medical School at Houston, Houston, TX, USA.; Gregory W Albers, MD, Director, Stanford Stroke Center; Coyote Foundation Professor of Neurology and Neurological Sciences
      ; Joseph P Broderick, MD, Director of the Greater Cincinnati-Northern Kentucky Stroke Team; Professor and Chairman, University of Cincinnati, Department of Neurology and Rehabilitation Medicine, Cincinnati, OH
      ; Scott E Kasner, MD, MSCE, FRCP, Professor of Neurology at the Hospital of the University of Pennsylvania, Philadelphia, PA; Eng H Lo, PhD, Professor of Neuroscience, Harvard Medical School; Head, Neuroprotection Research Lab, Massachusetts General Hospital, Charlestown, MA
      ; A David Mendelow, MB BCh, FRCS, PhD, William Leech Professor of Neurosurgery, Newcastle University, UK
      ; Ralph L Sacco, MD MS FAHA FAAN, Olemberg Chair of Neurology and Professor of Neurology, Epidemiology and Public Health, Human Genetics, and Neurological Surgery, University of Miami Miller School of Medicine, Miami, FL
      and Lawrence KS Wong, MD, FRCP, Mok Hing Yiu Professor of Medicine, Chief of Neurology, Departments of Medicine and Therapeutics, Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong, PR China




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