Zipes and Jalife's Cardiac Electrophysiology: From Cell to Bedside, 8th Edition

Edited by Jose Jalife, MD, PhD and William Gregory Stevenson, MD
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Fully updated from cover to cover, Zipes and Jalife's Cardiac Electrophysiology: From Cell to Bedside, 8th Edition, provides the comprehensive, multidisciplinary coverage you need-from new knowledge in basic science to the latest clinical advances in the field. Drs. José Jalife and William Gregory Stevenson lead a team of global experts who provide cutting-edge content and step-by-step instructions for all aspects of cardiac electrophysiology. 

  • Packs each chapter with the latest information necessary for optimal basic research as well as patient care. 

  • Covers new technologies such as CRISPR, protein research, improved cardiac imaging, optical mapping, and wearable devices. 

  • Contains significant updates in the areas of molecular biology and genetics, iPSCs (induced pluripotent stem cells), embryonic stem cells, precision medicine, antiarrhythmic drug therapy,  cardiac mapping with advanced techniques, and ablation technologies including stereotactic radioablation. 

  • Includes 47 new chapters covering both basic science and clinical topics. 

  • Discusses extensive recent progress in the understanding, diagnosis, and management of arrhythmias, including new clinical insights on atrial fibrillation and stroke prevention, new advances in the understanding of ventricular arrythmias in genetic disease, and advances in implantable devises and infection management. 

  • Features 1,600 high-quality photographs, anatomic and radiographic images, electrocardiograms, tables, algorithms, and more., with additional figures, tables, and videos online. 

  • Recipient of a 2018 Highly Commended award from the British Medical Association. 

  • Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.

ISBN 9780323757454
Author Information By Jose Jalife, MD, Cyrus and Jane Farrehi Professor of Cardiovascular Research,Department of Internal Medicine, Professor of Molecular and Integrative Physiology, Co-Director for Arrhythmia Research, University of Michigan, Ann Arbor, Michigan Senior Investigator, Fundacion Centro Nacional De Investigaciones Cardiovascularres (CNIC), Madrid, Spain and William Gregory Stevenson, MD, Director, Cardiac Arrhythmia Program, Cardiovascular Division, Brigham and Women's Hospital; Professor of Medicine Harvard Medical School, Boston, MA
Table of Content 1        Voltage-Gated Sodium Channels and Electrical Excitability of the Heart
2        Voltage-Gated Calcium Channels
3        Voltage-Regulated Potassium Channels
4        Molecular Regulation of Cardiac Inward Rectifier Potassium Channel
5        Mammalian Calcium Pumps in Health and Disease
6        Structural and Molecular Bases of Sarcoplasmic Reticulum Ion Channel Function
7        Organellar Ion Channels and Transporters
8        Gap Junctional Connexin 43: Novel Insights from the New Millennium and their Clinical Implications
9        Computational modeling and simulation for human cardiac electrophysiology: From induced pluripotent stem-cell derived cardiomyocytes to adult cardiomyocytes
10      Regulation of Cardiac Calcium Channels
11      Molecular Genetics of ATP-Sensitive Potassium Channels in Cardiovascular Diseases
12      Role of Enhancers in Transcriptional Regulation of Cardiac Electrical Activity
13      Functional characterization of ion channel gene variants in sudden unexplained natural death
14      Stretch-Activated Potassium Channels in the Human Heart: Pathophysiologic and Clinical Significance
15      Connexins and Pannexins in Cardiovascular Disease
16      Excitation-Contraction Coupling
17      Ion Channel Trafficking in the Heart
17      Ion Channel Trafficking in the Heart
18      Microdomain Interactions of Macromolecular Complexes and Regulation of the Sodium Channel Nav1.5
19      Connecting Cardiac Excitation to the Atomic Interactions of Ion Channels
20      Macromolecular Complexes and Cardiac Potassium Channels
21      Reciprocity of Cardiac Sodium and Potassium Channels in the Control of Excitability and Arrhythmias
22      The Intercalated Disc: A Molecular Network That Integrates Electrical Coupling, Intercellular Adhesion and Cell Excitability
23      Function and Dysfunction of Ion Channel Membrane Trafficking and Post Translational Modification
24      Feedback Mechanisms for Cardiac-Specific microRNAs and cAMP Signaling in Electrical Remodeling
25      Coupled Oscillators and Sinoatrial Pacemaker Activity
25      Coupled Oscillators and Sinoatrial Pacemaker Activity
26      Mapping of Cardiac Action Potentials in Zebrafish to Assess Genetic Variants
27      Cell-to-Cell Communication and Impulse Propagation
28      Mechanisms of Normal and Dysfunctional Sinoatrial Nodal Excitability and Propagation
29      Cell Biology of the Specialized Cardiac Conduction System
30      Computational Predictions of Drug-Induced Arrhythmias
31      Global Optimization Approaches to Generate Dynamically Robust Electrophysiological Models
32      Calcium Signaling in Cardiomyocyte Models with Realistic Geometries
33      Theory of Rotors and Arrhythmias
34      Distinct ECG Phenotypes Identified in Hypertrophic Cardiomyopathy Using Machine Learning Associated with Arrhythmic Risk Markers
35      Computational Approaches for Accurate Rotor localization in the Human Atria
36      Modeling the Aging Heart
37      Electromechanical Vortex Filaments During Cardiac Fibrillation
38      Innervation of the Sinoatrial Node
39      Autonomic and Oxidant Regulation of Cardiac Sodium Currents: Mechanisms and Consequences
40       Neural Activity and Atrial Tachyarrhythmias
41       Sympathetic Modulation of Cardiac Electrophysiology
42       Role of the Autonomic Nervous System in Atrial Fibrillation
43       Rotational and Focal Sources of Atrial Fibrillation:  Scientific Rationale and Comparative Clinical Mapping
44       Nonivasive Frequency-Phase Mapping of Atrial Fibrillation
45       Mechanistic approaches for persistent AF ablation
46       Mechanisms of Human Ventricular Tachycardia and Human Ventricular Fibrillation
47       Genetics of Atrial Fibrillation
48       Mechanisms in Genetic Sodium Channel Diseases
49      Genetic, Ionic and Cellular Mechanisms Underlying the J Wave Syndromes
50      Inheritable Potassium Channel Diseases
51      Inheritable Phenotypes Associated With Altered Intracellular Calcium Regulation
52      Dominant Frequency as a Tool for Personalized Monitoring of Atrial fibrillation Progression and Upstream Therapy
53      Pharmacogenomics of Cardiac Arrhythmias
54      Screening Drugs for Myocardial Disease in Vivo with Zebrafish
55      Gene Therapy for Atrial Fibrillation
56      Cardiac Remodeling and Regeneration
57      High-Throughput Optical Mapping of 2-Dimensional hiPSC-CM Platforms for Drug Discovery and Cardiotoxicity Testing
58      Functional Cardiac Fibroblasts Derived from Human Pluripotent Stem Cells via Second Heart Field Progenitors
59      The challenges of human iPSC-CM technology: Increasingly complex approaches improve cell maturation and relevance to modelling human cardiac disease
60      Assessment of the Patient With a Cardiac Arrhythmia
61      Differential Diagnosis of Narrow and Wide Complex Tachycardias
62       Electrocardiographic Monitoring: Short,  Long-Term Recording
63       Personal Cardiac Monitoring
64       Computed Tomography for Electrophysiology
65       Magnetic Resonance Imaging for Electrophysiology
66       Intracardiac Echocardiography for Electrophysiology
67       Autonomic Nervous System Assessment for Syncope and Arrhythmia Risk
68       Noninvasive Electrocardiographic Imaging of Arrhythmogenic Substrates and Arrhythmias
69       Genetic Testing
70       Supraventricular Tachycardias:  Diagnostic Maneuvers in the Electrophysiology Laboratory
71       Atrial Tachycardia
72       Atrioventricular Nodal Reentrant Tachycardia
73       Junctional Tachycardia
74       Preexcitation, Atrioventricular Reentry, Variants
75       Atrial Fibrillation: Mechanisms, Clinical Features, and Management
76       Ablation for Atrial Fibrillation
77        Left Atrial Appendage Management
78        Typical and Atypical Atrial Flutter: Mapping and Ablation
79         Sudden Cardiac Death in Adults
80         Premature Ventricular Complexes
81         Outflow Tract Ventricular Tachyarrhythmias: Mechanisms, Clinical Features, and Management
82         PVC Ablation with Anatomic Guidance:  Papillary Muscle, Moderator Band and Valve Annulus Sites
83         Fascicular Ventricular Arrhythmias
84         Bundle Branch Reentry Tachycardia
85         Ischemic Heart Disease
86         Ablation of Post-Myocardial Infarction Ventricular Tachycardia 
87         Ventricular Tachycardia in Patients with Dilated Cardiomyopathy
88         Lamin A/C, Noncompaction and Other Genetic Cardiomyopathies with Ventricular Arrhythmias
89         Ventricular Arrhythmias in Hypertrophic Cardiomyopathy: Sudden Death, Risk Stratification, and Prevention With Implantable Defibrillators
90         Ventricular Tachycardias in Arrhythmogenic Right Ventricular Dysplasia/Cardiomyopathy
91         Catecholaminergic Polymorphic Ventricular Tachycardia
92         Arrhythmias and Conduction Disturbances in Noncompaction Cardiomyopathy
93          Ventricular Arrhythmias in Takotsubo Cardiomyopathy
94           Mitral Valve Prolapse, ventricular arrhythmias and Sudden Death
95           Brugada Syndrome
96           Long and Short QT Syndromes
97          Andersen-Tawil Syndrome
98          Timothy Syndrome
99          J-Wave Syndromes
100        Idiopathic and Short-Coupled Ventricular Fibrillation
101        Mapping and Ablation of Ventricular Fibrillation
102        Drug-Induced Ventricular Arrhythmias
103        Syncope
104        Sinus Node Abnormalities
105        Postural Orthostatic Tachycardia Syndrome
106        Atrioventricular Block
107        Sex Differences in Arrhythmias
108        Sudden Cardiac Deaths in Athletes, Including Commotio Cordis
109        Cardiac Sarcoidosis
110        Sleep-Disordered Breathing and Arrhythmias
111        Ventricular Assist Devices and Cardiac Transplant Recipients
112        Arrhythmia in Neurologic Disease
113        Cancer Therapy Related Arrhythmias
114        Arrhythmias in the Pediatric Population
115        Supraventricular Tachycardias in Congenital Heart Disease
116        Ventricular Arrhythmias in Congenital Heart Disease
117        Antiarrhythmic Drugs
118        Impact of Nontraditional Antiarrhythmic Drugs on Sudden Cardiac Death
119        Oral Anticoagulants
120         Implantable Pacemakers
121         Implantable Cardioverter Defibrillators: Technical Aspects
122        Transvenous Implantable Cardioverter Defibrillator: Clinical Aspects
123        Subcutaneous Implantable Cardioverter Defibrillators
124        Wearable Defibrillators
125        Cardiac Resynchronization
126        Management of Implanted Device Infections
127        Electrogram Recording and Signal Processing
128        Electroanatomic Mapping for Arrhythmias
129        Mapping Scar-Related Arrhythmias
130        Radiofrequency Ablation
131        Cryoablation and Other Radiofrequency Alternatives
132        Transvascular Ethanol Ablation
133       Cardiac Radioablation
134       Epicardial Approach in Electrophysiology
135       Surgery for Atrial Fibrillation and Other Supraventricular Tachycardias
136       Surgery for Ventricular Arrhythmias
137       Neuromodulation for the Treatment of Arrhythmias
発行日 17-12-2021
Pages 1392
trim 276 x 216 (8 1/2 x 10 7/8)
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